*{box-sizing:border-box}body{margin:0;padding:30px;color:#1f2937;background:#f8fafc}.container{max-width:1150px;margin:auto;padding:28px}h1{font-size:30px;margin:0 0 .67em}h2{font-size:24px;margin:28px 0 .83em}h3{font-size:18px}.intro{max-width:78ch;line-height:1.6;color:#475569}.top-actions{display:flex;align-items:center;gap:20px}.top-actions a{color:#315fc3;font-weight:600}.draft{margin-left:auto;font-size:12px;border:1px solid #cbd5e1;padding:5px 9px;border-radius:5px;color:#475569}.container section{margin:24px 0;padding:0}label{display:block;font-size:16px;font-weight:700;margin:16px 0 6px}input,select,textarea{display:block;width:100%;min-width:0;padding:10px;border:1px solid #cbd5e1;border-radius:8px;font-size:16px;color:inherit}textarea{font-family:ui-monospace,Consolas,monospace;min-height:170px;resize:vertical}button{background:#315fc3;color:#fff;border:0;border-radius:8px;padding:10px 15px;cursor:pointer;font:inherit;font-size:14px;font-weight:700}button.secondary{background:var(--action-primary)}button.copy-btn{background:#2f7d50}button:disabled{opacity:.5;cursor:default}.grid{display:grid;grid-template-columns:1fr 1fr;gap:12px 24px}.grid.three{grid-template-columns:repeat(3,1fr)}.grid>div{min-width:0}.inline{display:flex;gap:8px}.inline input{flex:1}.inline button{white-space:nowrap}.small{font-size:14px;color:#555;line-height:1.45}.section-heading{display:flex;align-items:center;justify-content:space-between;gap:12px}.section-heading h2{margin:0}.fragment{padding:15px 0;border-bottom:1px solid #dbe3ef}.fragment-head{display:flex;align-items:center;justify-content:space-between;gap:10px}.fragment-actions{display:flex;gap:6px}.fragment-actions button{padding:6px 10px}details{margin:16px 0;padding:12px 0;border-bottom:1px solid #dbe3ef}summary{cursor:pointer;font-size:14px;font-weight:700;color:#334155}details[open] summary{margin-bottom:12px}.actions{display:flex;gap:10px;flex-wrap:wrap;margin-top:20px}.error{color:#9f2626;background:#fff1f2;padding:14px;border:1px solid #fecdd3;border-radius:8px}.notice{background:#fff3cd;padding:10px;border:1px solid #ffe08a;border-radius:8px;font-size:14px;line-height:1.5}.construct-map{display:flex;gap:4px;flex-wrap:wrap;margin:18px 0}.construct-map span{border-top:5px solid var(--segment,#315fc3);background:#eef2f8;padding:12px 16px;flex:1;min-width:130px;font-size:14px;overflow-wrap:anywhere}.construct-map small{display:block;color:#475569;margin-top:4px}.table-wrap{overflow:auto}table{border-collapse:collapse;width:100%;font-size:14px;background:#fff}th,td{text-align:left;vertical-align:top;padding:9px;border:1px solid #ddd}th{background:#f1f5f9}td oligo,td .oligo{display:block;min-width:200px;max-width:540px;overflow-wrap:anywhere;font-family:ui-monospace,Consolas,monospace;line-height:1.6}td .tail,.tail-key{color:#2356ba;font-weight:700}.junction{padding:10px 0;border-bottom:1px solid #e2e8f0}.junction code{display:block;overflow-wrap:anywhere;margin-top:6px}pre{white-space:pre-wrap;overflow-wrap:anywhere;font-size:13px;line-height:1.6}footer{margin:35px 0 10px;font-size:13px}[hidden]{display:none!important}@media(max-width:650px){body{padding:14px}.container{padding:14px}.grid,.grid.three{grid-template-columns:1fr;gap:3px}h1{font-size:26px}.top-actions{gap:12px}.draft{font-size:11px}.fragment-head{align-items:flex-start}.fragment-actions{flex-wrap:wrap;justify-content:flex-end}.section-heading{align-items:flex-start}.inline{flex-wrap:wrap}.inline input{min-width:90px}section{padding-top:20px}th,td{padding:9px}}

.top-actions{margin-bottom:18px;gap:10px;flex-wrap:wrap}.top-actions a{display:inline-flex;align-items:center;justify-content:center;min-height:34px;padding:8px 14px;border-radius:8px;color:#fff;text-decoration:none;font-size:14px;font-weight:600}.top-actions .faq-nav-btn{margin-left:auto}.top-actions a:focus-visible{outline:3px solid #315fc3;outline-offset:3px}.small[data-seo-intro]{max-width:96ch;line-height:1.6}.container label{font-size:16px}.method-references{padding:18px 20px}footer{text-align:center;margin:28px auto;max-width:1150px}footer a{color:#1d4ed8}.container li{line-height:1.6;margin:7px 0}.container>p{line-height:1.6}.container textarea{font-family:ui-monospace,Consolas,monospace}.draft{display:none}@media(max-width:650px){.method-references{padding:16px 14px}.top-actions a{padding:7px 10px}.container h2{font-size:21px}}

/* Guides have four navigation links; wrap when their available width runs out. */
body[data-page-kind=help] .top-actions{flex-wrap:wrap!important}
.back-to-top-btn{position:fixed;right:22px;bottom:22px;width:46px;height:46px;border-radius:50%;padding:0;font-size:24px;z-index:20}

.junction-input{padding:12px 0;border-bottom:1px solid #dbe3ef;min-width:0}.junction-input:last-child{border-bottom:0}.junction-input>strong{display:block;font-size:15px;overflow-wrap:anywhere}.junction-fields{display:grid;grid-template-columns:minmax(130px,180px) minmax(0,1fr);gap:12px 24px}.junction-fields>div{min-width:0}.junction-linker{font-family:ui-monospace,Consolas,monospace}@media(max-width:650px){.junction-fields{grid-template-columns:1fr;gap:3px}}

/* Preserve the site action palette by function. */


.sequence-summary{margin-top:8px;padding:9px 11px;border-radius:8px;font-size:14px}.sequence-summary:empty{display:none}.summary-ok{background:#dcfce7;border:1px solid #86efac;color:#166534}

button[type=submit]{padding:12px 22px;font-size:16px}.sequence-summary{line-height:1.45}.summary-error{background:#ffe4e6;border:1px solid #fb7185;color:#9f1239}body[data-page-kind=help]>.container,body[data-page-kind=help]>.method-references{max-width:1050px}body[data-page-kind=help] .container h1{font-size:32px;line-height:1.2}body[data-page-kind=help] .container h2{font-size:22px}body[data-page-kind=help] .container :is(p,li){font-size:16px;line-height:1.55}@media(max-width:800px){body{padding:12px}.container{padding:20px}.grid,.grid.three{grid-template-columns:1fr}.junction-fields{grid-template-columns:1fr}body[data-page-kind=help] .container h1{font-size:28px}}

button:is(#addFragment,#addEdit){background:var(--action-primary)}button:is(#addFragment,#addEdit):hover{background:var(--action-primary-hover)}button[id^=download]{background:var(--action-success)}button[id^=download]:hover{background:var(--action-success-active)}button:is(.remove-fragment,.remove-edit){background:#dc2626;color:#fff;font-family:Arial,sans-serif;font-size:18px;line-height:1;padding:4px 10px;border-radius:8px;width:auto;justify-self:end;align-self:center}button:is(.move-up,.move-down,#resetOverlap){background:var(--action-neutral)}

/* Compact entry rows; add actions follow the list they extend. */
.add-item-btn{display:inline-block;width:auto;margin-top:14px;padding:10px 14px;font-size:14px;line-height:18px;background:var(--action-primary)}
.add-item-btn:hover{background:var(--action-primary-hover)}
.vector-file-row{display:flex;align-items:flex-start;flex-wrap:wrap;gap:12px 24px}
.vector-file-row .file-control{width:280px;max-width:100%}
.vector-file-row .position-control{width:360px;max-width:100%}
.position-control input{width:130px;max-width:100%}
.position-control .small{margin:6px 0 0}
.fragment-options{display:grid;grid-template-columns:minmax(0,280px) 120px minmax(0,400px);gap:12px 20px;align-items:start}
.fragment-options>.fragment-junction{display:contents}
.fragment-options>div,.fragment-options .fragment-junction>div{min-width:0}
.fragment-options .junction-overlap{width:110px;max-width:100%}
.fragment-options input[type=file],.vector-file-row input[type=file]{max-width:100%;overflow:hidden}
.compact-primer-settings>.grid{display:flex;flex-wrap:wrap;align-items:flex-start;gap:12px 24px}
.compact-primer-settings>.grid>div{flex:0 1 auto;min-width:0;max-width:100%}
.compact-primer-settings input{width:120px;max-width:100%}
.compact-primer-settings .small{max-width:235px;margin:6px 0 0}
.mutation-controls{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:28px}
.container .mutation-controls>section{margin:0}
.mutation-controls h2{margin-top:24px}
.mutation-row{display:grid;grid-template-columns:130px 120px 120px 30px;gap:12px;align-items:start;padding:0 0 12px;border-bottom:1px solid #dbe3ef}
.mutation-row>div{min-width:0}
.mutation-row button.remove-edit{margin-top:48px;align-self:start}
.mutation-row .base-hint{display:block;margin-top:4px}
.mutation-controls #editsHelp{margin:8px 0 0}
@media(max-width:1050px){.mutation-controls{grid-template-columns:1fr}.mutation-row{max-width:100%}.fragment-options{grid-template-columns:minmax(0,240px) 110px minmax(0,1fr);gap:12px 16px}}
@media(max-width:800px){.fragment-options{grid-template-columns:110px minmax(0,1fr);gap:3px 16px}.fragment-upload{grid-column:1/-1;max-width:280px}.fragment-options .junction-linker{width:100%}.mutation-controls{gap:0}}
@media(max-width:540px){.mutation-row{grid-template-columns:minmax(0,1fr) minmax(0,1fr) minmax(0,1fr) 30px;gap:8px}.mutation-row label{font-size:14px;min-height:34px}.mutation-row button.remove-edit{margin-top:63px}.mutation-row input,.mutation-row select{padding:10px 6px}.compact-primer-settings>.grid{gap:12px 18px}.fragment-options{grid-template-columns:90px minmax(0,1fr);gap:3px 12px}.fragment-options .junction-overlap{width:90px}.fragment-options label{font-size:14px;min-height:34px}.fragment-upload label{min-height:0}.vector-file-row{gap:0}.position-control label{font-size:14px}.position-control .small{max-width:32ch}}
@media(max-width:540px){.mutation-row label,.fragment-options label{line-height:18px;min-height:36px}.fragment-upload label{min-height:0}.mutation-row button.remove-edit{margin-top:66px}}
@media(max-width:380px){.mutation-row{grid-template-columns:minmax(0,1fr) minmax(0,1fr) 30px}.mutation-row>div:first-child{grid-column:1/-1;width:120px}.mutation-row label{min-height:0}.mutation-row button.remove-edit{margin-top:48px}}